By A. P. Cawadias, 1946
PREFACE TO THE SECOND EDITION: The object of this work has been the isolation of groups of inter- sexes possessing common clinical features and arising from particular physiopathological disturbances, i.e., from particular modes of malfunction oft h e mechanism of sex determination. For this reason I have studied first the physiopathology of intersexuality. To orient myself in the maze of experimental research towards a synthetic conception useful for clinical work, I followed not only the natural historical approach but also the cultural historical approach, which I believe to be a necessary complement to the natural historical method.